Structure. The largest and most medial of the three longitudinal frontal convolutions. Laterally it runs from the frontopolar region back to the precentral sulcus, bounded below by the superior frontal sulcus (with its accessory parts); medially it is continuous with its medial part around the superior margin of the hemisphere. Its rostral two-thirds are heteromodal association cortex; its most posterior dorsal bend approaches the supplementary motor and frontal-eye-field region.
Function. Rostral (prefrontal) territory: working memory, task-set maintenance and executive control — the dorsolateral prefrontal band. The caudal-dorsal portion participates in oculomotor control (frontal eye field) and in the frontoparietal control network identified by intrinsic connectivity, which bridges external-attention and default-mode systems.
| Instrument | Role | Tier | Credibility | Via | Observed effect |
|---|---|---|---|---|---|
| nback ↗ | assessor | secondary | standard-scientific | fMRI | Intrinsic fMRI in children and adolescents ties left superior frontal gyrus activity (degree centrality and fA |
| stopsignal ↗ | assessor | secondary | standard-scientific | fMRI | Stop-signal fMRI: controls preactivate left superior frontal gyrus (-19, 64, 19; Z=12.99) during prospective i |
| pain-induction | assessor | secondary | standard-scientific | fMRI | Vicarious-pain fMRI: watching a confederate receive a noxious shock engages left superior frontal gyrus (-12, |
| facial-emotion | assessor | secondary | standard-scientific | fMRI | Emotional Faces Shifting Attention Task fMRI: a group-by-emotion interaction appears in superior frontal gyrus |
| reward-prediction ↗ | assessor | secondary | standard-scientific | fMRI | The region's Neurosynth decode ranks 'reward' 5th of 250 terms (association 0.0069), with 'feedback' (0.0044) |
| cyberball ↗ | assessor | secondary | standard-scientific | fMRI | Decode ranks 'self' 2nd (0.010) - the region's second-strongest association - with 'social' (0.0042) and 'tom' |
| stopsignal ↗ | stimulator | secondary | standard-scientific | delivery | Healthy adolescent controls withholding a response ahead of the stop signal (prospective inhibition) recruited |
| reward-punishment ↗ | stimulator | secondary | standard-scientific | delivery | During fMRI with appetitive, aversive and neutral sights and tastes, superior frontal gyrus was listed first a |
| emotional-stroop ↗ | stimulator | secondary | standard-scientific | delivery | Profile ground: decoded terms 'negative' (w=0.0066, rank 8) and 'positive' (w=0.0054, rank 12) tie sfg-l's hel |
| nback ↗ | stimulator | secondary | standard-scientific | delivery | Profile ground: 'memory' is the 4th decoded term (w=0.0073) of sfg-l's held evidence; the n-back is the batter |
| stopsignal ↗ | inhibitor | secondary | standard-scientific | delivery | ICA/fALFF of the stop-signal task (76 subjects): left superior frontal cortex showed greater low-frequency act |
| nback ↗ | inhibitor | secondary | standard-scientific | delivery | Profile ground: 'default' (w=0.0083, rank 3) and 'dmn' (w=0.0063, rank 10) decode sfg-l as default-mode tissue |
| flanker ↗ | stimulator | secondary | standard-scientific | delivery | In healthy controls on the Attention Network Test, the flanker-conflict contrast (incongruent>congruent) activ |
| stroop ↗ | inhibitor | secondary | standard-scientific | delivery | During a self-paced Stroop task, congruent blocks deactivated left dorsal medial frontal cortex (BA 8; -18,24, |
| facial-emotion | inhibitor | secondary | standard-scientific | delivery | Emotional face matching (Hariri paradigm) deactivated left superior frontal cortex (BA 8; -20,25,44; T=11.30, |
| pain-induction | inhibitor | secondary | standard-scientific | delivery | Needle somatosensory stimulation at acupuncture point ST36 and two non-acupoint control points deactivated lef |
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| 24-h smoking abstinence potentiates fMRI-BOLD activation to smoking cues in cerebral cortex and dorsal striatum. Psychopharmacology 2009 · 10.1007/s00213-008-1436-9 |
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| Sustained activity within the default mode network during an implicit memory task. Cortex; a journal devoted to the study of the nervous system and behavior 2010 · 10.1016/j.cortex.2009.05.002 |
| Neural correlates of processing stressful information: an event-related fMRI study. Brain research 2009 · 10.1016/j.brainres.2009.06.044 |
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| Neural correlates of evaluative compared with passive tasting. The European journal of neuroscience 2009 · 10.1111/j.1460-9568.2009.06819.x |
| Left cytoarchitectonic area 44 supports selection in the mental lexicon during language production. Brain structure & function 2009 · 10.1007/s00429-009-0213-9 |
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| The unrested resting brain: sleep deprivation alters activity within the default-mode network. Journal of cognitive neuroscience 2010 · 10.1162/jocn.2009.21331 |
| The effects of psychotherapy on neural responses to rewards in major depression. Biological psychiatry 2009 · 10.1016/j.biopsych.2009.06.021 |
| Motivational orientation modulates the neural response to reward. NeuroImage 2010 · 10.1016/j.neuroimage.2009.09.013 |
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| Temporal order processing of syllables in the left parietal lobe. The Journal of neuroscience : the official journal of the Society for Neuroscience 2009 · 10.1523/JNEUROSCI.5934-08.2009 |
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| Dissociable neural circuits for encoding and retrieval of object locations during active navigation in humans. NeuroImage 2010 · 10.1016/j.neuroimage.2009.10.021 |
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| Minds made for sharing: initiating joint attention recruits reward-related neurocircuitry. Journal of cognitive neuroscience 2010 · 10.1162/jocn.2009.21401 |
| Functional variation of the dopamine D2 receptor gene is associated with emotional control as well as brain activity and The Journal of neuroscience : the official journal of the Society for Neuroscience 2009 · 10.1523/JNEUROSCI.3609-09.2009 |
| Exploring the brain in pain: activations, deactivations and their relation. Pain 2010 · 10.1016/j.pain.2009.11.008 |
| Structural neuroplasticity in the sensorimotor network of professional female ballet dancers. Human brain mapping 2010 · 10.1002/hbm.20928 |
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| Brain regions involved in the learning and application of reward rules in a two-deck gambling task. Neuropsychologia 2010 · 10.1016/j.neuropsychologia.2010.01.012 |
| Delineating self-referential processing from episodic memory retrieval: common and dissociable networks. NeuroImage 2010 · 10.1016/j.neuroimage.2010.01.087 |
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| From moral to legal judgment: the influence of normative context in lawyers and other academics. Social cognitive and affective neuroscience 2011 · 10.1093/scan/nsq010 |
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| How the brain handles temporally uncoupled bimanual movements. Cerebral cortex (New York, N.Y. : 1991) 2010 · 10.1093/cercor/bhq048 |
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| Neural responses to unattended products predict later consumer choices. The Journal of neuroscience : the official journal of the Society for Neuroscience 2010 · 10.1523/JNEUROSCI.0064-10.2010 |
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| An event-related FMRI study of phonological verbal working memory in schizophrenia. PloS one 2010 · 10.1371/journal.pone.0012068 |
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| Projecting memories: the role of the hippocampus in emotional mentalizing. NeuroImage 2011 · 10.1016/j.neuroimage.2010.08.057 |
| Neuroimaging reveals dual routes to reading in simultaneous proficient readers of two orthographies. NeuroImage 2011 · 10.1016/j.neuroimage.2010.09.022 |
| Mapping anterior temporal lobe language areas with fMRI: a multicenter normative study. NeuroImage 2011 · 10.1016/j.neuroimage.2010.09.048 |
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| Prefrontal and medial temporal lobe activity at encoding predicts temporal context memory. The Journal of neuroscience : the official journal of the Society for Neuroscience 2010 · 10.1523/JNEUROSCI.1337-10.2010 |
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| Amygdala activity at encoding corresponds with memory vividness and with memory for select episodic details. Neuropsychologia 2011 · 10.1016/j.neuropsychologia.2011.01.017 |
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| Effect of emotional valence on retrieval-related recapitulation of encoding activity in the ventral visual stream PMID 26459096 |
| Preschoolers' brains rely on semantic cues prior to the mastery of syntax during sentence comprehension PMID 26497266 |
| Evidence Accumulation and Choice Maintenance Are Dissociated in Human Perceptual Decision Making PMID 26510176 |
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| Resting-State Functional Network Connectivity in Prefrontal Regions Differs Between Unmedicated Patients with Bipolar an PMID 26551408 |
| Comprehension through explanation as the interaction of the brain’s coherence and cognitive control networks PMID 26557066 |
| Laterality effects in functional connectivity of the angular gyrus during rest and episodic retrieval PMID 26559474 |
| Mindfulness Meditation-Based Pain Relief Employs Different Neural Mechanisms Than Placebo and Sham Mindfulness Meditatio PMID 26586819 |
| Frontal gray matter abnormalities predict seizure outcome in refractory temporal lobe epilepsy patients PMID 26594628 |
| Neural correlates of event clusters in past and future thoughts: How the brain integrates specific episodes with autobio PMID 26658926 |
| Multivariate pattern analysis of obsessive–compulsive disorder using structural neuroanatomy PMID 26708318 |
| Implicit and Explicit Attention to Pictures and Words: An fMRI-Study of Concurrent Emotional Stimulus Processing PMID 26733895 |
| Functional connectivity of the amygdala and subgenual cingulate during cognitive reappraisal of emotions in children wit PMID 26746624 |
| Influence of the cortical midline structures on moral emotion and motivation in moral decision-making PMID 26772629 |
| Gray Matter Volume and Resting-State Functional Connectivity of the Motor Cortex-Cerebellum Network Reflect the Individu PMID 26779015 |
| Altered balance of functional brain networks in Schizophrenia PMID 26786152 |
| An fMRI study of perception and action in deaf signers PMID 26796716 |
| Evaluating cognitive models of visual word recognition using fMRI: Effects of lexical and sublexical variables PMID 26806289 |
| Alterations of functional connectivities from early to middle adulthood: Clues from multivariate pattern analysis of res PMID 26825442 |
| Decreased Fronto-Limbic Activation and Disrupted Semantic-Cued List Learning in Major Depressive Disorder PMID 26831638 |
| Abnormal spontaneous brain activity in type 2 diabetes with and without microangiopathy revealed by regional homogeneity PMID 26860674 |
| Language comprehension and brain function in individuals with an optimal outcome from autism PMID 26862477 |
| Post mTBI fatigue is associated with abnormal brain functional connectivity PMID 26878885 |
| Age-related changes in overcoming proactive interference in associative memory: The role of PFC-mediated executive contr PMID 26879623 |
| Early dysfunctions of fronto-parietal praxis networks in Parkinson’s disease PMID 26935551 |
| Correlation between amygdala BOLD activity and frontal EEG asymmetry during real-time fMRI neurofeedback training in pat PMID 26958462 |
| Cough Is Dangerous: Neural Correlates of Implicit Body Symptoms Associations PMID 26973558 |
| Maternal sensitivity and the empathic brain: Influences of early life maltreatment PMID 26985733 |
| Calcitonin Gene-Related Peptide Modulates Heat Nociception in the Human Brain - An fMRI Study in Healthy Volunteers PMID 26990646 |
| Decreased gray matter volume is associated with the subtypes of psychotic symptoms in patients with antipsychotic-naïve PMID 27000306 |
| Functional brain substrate of quality of life in patients with schizophrenia: A brain SPECT multidimensional analysis PMID 27000309 |
| Context-Dependent Neural Modulations in the Perception of Duration PMID 27013993 |
| Mindful attention to breath regulates emotions via increased amygdala–prefrontal cortex connectivity PMID 27033686 |
| Functional Magnetic Resonance Imaging Study of Brain Activity Associated With Pitch Adaptation During Phonation in Healt PMID 27049447 |
| The Neural Correlates of Long-Term Carryover following Functional Electrical Stimulation for Stroke PMID 27073701 |
| Effects of serotonin 2A/1A receptor stimulation on social exclusion processing PMID 27091970 |
| Working Memory Network Changes in ALS: An fMRI Study PMID 27147950 |
| The involvement of the fronto-parietal brain network in oculomotor sequence learning using fMRI PMID 27157884 |
| Task and Resting-State fMRI Reveal Altered Salience Responses to Positive Stimuli in Patients with Major Depressive Diso PMID 27192082 |
| Reduced task-related functional connectivity during a set-shifting task in unmedicated early-stage Parkinson’s disease p PMID 27194153 |
| The Human Brainnetome Atlas: A New Brain Atlas Based on Connectional Architecture PMID 27230218 |
| Neurofeedback of visual food cue reactivity: a potential avenue to alter incentive sensitization and craving PMID 27233784 |
| Characterizing cerebellar activity during autobiographical memory retrieval: ALE and functional connectivity investigati PMID 27235570 |
| A pilot study of changes in functional brain activity during a working memory task after mSMT treatment: The MEMREHAB tr PMID 27237764 |
| Small Changes, But Huge Impact? The Right Anterior Insula's Loss of Connection Strength during the Transition of Old to PMID 27242508 |
| Perceptual demand and distraction interactions mediated by task-control networks PMID 27261159 |
| Effects of progressive muscle relaxation on cerebral activity: An fMRI investigation PMID 27261979 |
| Brain activation profiles during kinesthetic and visual imagery: An fMRI study PMID 27288703 |
| Interaction between episodic and semantic memory networks in the acquisition and consolidation of novel spoken words PMID 27291335 |
| Previous Institutionalization Is Followed by Broader Amygdala–Hippocampal–PFC Network Connectivity during Aversive Learn PMID 27307231 |
| Temporal dynamics of brain activation during 40 minutes of pleasant touch PMID 27338514 |
| Decreased neural response for facial emotion processing in subjects with high genetic load for schizophrenia PMID 27375133 |
| Temporo-parietal connectivity uniquely predicts reading change from childhood to adolescence PMID 27377221 |
| Neural correlates of mindful self-awareness in mindfulness meditators and meditation-naïve subjects revisited PMID 27377788 |
| The Association of Aging with White Matter Integrity and Functional Connectivity Hubs PMID 27378915 |
| Brain dynamics of post‐task resting state are influenced by expertise: Insights from baseball players PMID 27448098 |
| Tinnitus- related distress: evidence from fMRI of an emotional stroop task PMID 27499700 |
| Functional brain and age-related changes associated with congruency in task switching PMID 27520472 |
| Comparison of brain activation patterns during executive function tasks in hoarding disorder and non-hoarding OCD PMID 27522332 |
| Altered Development of Amygdala-Anterior Cingulate Cortex Connectivity in Anxious Youth and Young Adults PMID 27525316 |
| Neurocomputational mechanisms of prosocial learning and links to empathy PMID 27528669 |
| Distinct functional properties of the vertical and horizontal saccadic network in Health and Parkinson's disease: An eye PMID 27545665 |
| Mapping the brain correlates of borderline personality disorder: A functional neuroimaging meta-analysis of resting stat PMID 27552444 |
| The link between callous-unemotional traits and neural mechanisms of reward processing: An fMRI study PMID 27564545 |
| A spatial covariance 123I-5IA-85380 SPECT study of α4β2 nicotinic receptors in Alzheimer's disease PMID 27565302 |
| Episodic specificity induction impacts activity in a core brain network during construction of imagined future experienc PMID 27601666 |
| Altered Resting-State Functional Connectivity of the Striatum in Parkinson's Disease after Levodopa Administration PMID 27611959 |
| When opposites lead to the same: a direct comparison of explicit and implicit disgust regulation via fMRI PMID 27665000 |
| Bilateral parietal contributions to spatial language PMID 27690125 |
| The association of serotonin receptor 3A methylation with maternal violence exposure, neural activity, and child aggress PMID 27720744 |
| Learning and retrieving holistic and componential visual-verbal associations in reading and object naming PMID 27720949 |
| Association of FKBP5 polymorphisms and resting-state activity in a frontotemporal–parietal network PMID 27754486 |
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| Development of the Intrinsic Language Network in Preschool Children from Ages 3 to 5 Years PMID 27812160 |
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| Novelty Seeking, Harm Avoidance, and Cerebral Responses to Conflict Anticipation: An Exploratory Study PMID 27857686 |
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| Combined 18F-FDG-PET and diffusion tensor imaging in mesial temporal lobe epilepsy with hippocampal sclerosis PMID 27995064 |
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| Preliminary fMRI findings concerning the influence of 5‐HTPon food selection PMID 28127513 |
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| Neural mechanisms of implicit cognitive reappraisal: Preceding descriptions alter emotional response to unpleasant image PMID 28192177 |
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*Frontal lobe · Mai atlas of record · 665 studies · 149 papers on disk*
The superior frontal gyrus is the largest and most medial of the frontal lobe's three longitudinal convolutions — running from the frontopolar region to the precentral sulcus, carrying rostral prefrontal working-memory territory caudally and a medial default-mode-affective side whose decoded profile reads self, default, reward, negative emotion.
The largest and most medial of the three longitudinal frontal convolutions. Laterally it runs from the frontopolar region back to the precentral sulcus, bounded below by the superior frontal sulcus (with its accessory parts); medially it is continuous with its medial part around the superior margin of the hemisphere. Its rostral two-thirds are heteromodal association cortex; its most posterior dorsal bend approaches the supplementary motor and frontal-eye-field region.
*— {'source': 'Mai, Majtanik & Paxinos', 'work': 'Atlas of the Human Brain, 4th ed., Academic Press/Elsevier', 'kind': 'atlas', 'locator': 'axial plates, MNI y −19.7…+63.5 mm, 47 plates (labels SFG/SFGL/SFGM)'}*
Rostral (prefrontal) territory: working memory, task-set maintenance and executive control — the dorsolateral prefrontal band. The caudal-dorsal portion participates in oculomotor control (frontal eye field) and in the frontoparietal control network identified by intrinsic connectivity, which bridges external-attention and default-mode systems.
The functional record: rostral working-memory, task-set maintenance and executive control — the dorsolateral band; the caudal-dorsal portion joins oculomotor control. The decoded profile's default and self terms mark the medial wall's side: the SFG's medial bank participates in the default network's self-referential and affective traffic. No graded instrument is assigned to this dossier yet — the executive family's records live on the neighbouring BA 9, MFG and FEF dossiers; the SFG's own grading is an open slot.
*— {'source': 'Gazzaniga, Ivry & Mangun', 'work': 'Cognitive Neuroscience: The Biology of the Mind, 4th ed., W. W. Norton', 'kind': 'textbook', 'locator': 'ch. 12, Cognitive Control'}*
*— {'source': 'Yeo, Krienen, Sepulcre et al.', 'work': 'The organization of the human cerebral cortex estimated by intrinsic functional connectivity, J Neurophysiol 2011', 'locator': 'frontoparietal control network among the seven intrinsic networks', 'kind': 'paper'}*
Superior frontal sulcus (337 shared studies), isthmus of cingulate (293), angular gyrus (271), collateral sulcus (234) — a modest map for a large gyrus: its literature is scattered across the rostral prefrontal and medial-affective records.
Co-activation partners of record: Superior frontal sulcus:337, Isthmus of cingulate gyrus:293, Angular gyrus:271, Collateral sulcus:234, Inferior frontal gyrus, orbital part:232, Parahippocampal gyrus:230, Middle temporal gyrus:230, Amygdala:228.
The medial frontal lesions' apathy picture — the supplementary-motor-adjacent and anterior cingulate syndromes the SFG's medial bank borders. The decoded negative-emotion terms mark the medial-affective literature's depression findings.
10.1016/S0028-3932(01)00066-510.1016/S0896-6273(01)00519-010.1093/brain/awf19010.1016/S0006-3223(02)01488-9665 studies total touch this region in the Neurosynth corpus of record; the full literature lives beside this dossier.
Candidate levers (Neurosynth-decoded terms — network(anatomy-reference), self(method-other), default(cognition), memory(cognition), reward(method-other), networks(anatomy-reference), events(method-other), negative(emotion) …) are the foundation for the thousands of instruments to come; they are ungraded by law.
Superior frontal sulcus:337, Isthmus of cingulate gyrus:293, Angular gyrus:271, Collateral sulcus:234 — each name is a dossier stop in this explorer.