Structure. The precentral gyrus runs parallel to and immediately in front of the central sulcus, from the medial surface (continuous with the paracentral lobule) down toward the Sylvian fissure, bordered behind by the central sulcus and before by the precentral sulcus. Its layer V contains the giant Betz pyramidal cells; together with the posterior bank of the precentral sulcus it forms the primary motor area (Brodmann area 4), anterior to area 6.
Function. Primary motor cortex: the final somatotopically organized cortical stage for voluntary movement execution, projecting through the corticospinal tract. Intrinsic-connectivity parcellations place it at the core of the somatomotor network; stimulation evokes focal movements ordered as the motor homunculus. Lesion produces contralateral paresis of the represented body part.
| Instrument | Role | Tier | Credibility | Via | Observed effect |
|---|---|---|---|---|---|
| simple-rt ↗ | assessor | primary | highly-credible | fMRI | Contralateral primary motor cortex reads directly under imaging during finger response. |
| choice-rt ↗ | stimulator | secondary | standard-scientific | delivery | Selecting among alternatives adds premotor recruitment beyond simple response. |
| finger-sequence-learning | assessor | secondary | standard-scientific | fMRI | Primary motor engagement grows with sequence practice. |
| grip-force-tracking | assessor | secondary | standard-scientific | fMRI | M1 reads graded force output under imaging. |
| simple-rt ↗ | stimulator | secondary | standard-scientific | delivery | Co-engaged through the Motor system of record: the paradigm engages this system (its core members are graded e |
| choice-rt ↗ | assessor | secondary | standard-scientific | fMRI | Co-engaged through the Motor system of record: the paradigm engages this system (its core members are graded e |
| finger-sequence-learning | stimulator | secondary | standard-scientific | delivery | Co-engaged through the Motor system of record: the paradigm engages this system (its core members are graded e |
| motor-imagery | stimulator | secondary | standard-scientific | delivery | Co-engaged through the Motor system of record: the paradigm engages this system (its core members are graded e |
| motor-imagery | assessor | secondary | standard-scientific | fMRI | Co-engaged through the Motor system of record: the paradigm engages this system (its core members are graded e |
| grip-force-tracking | stimulator | secondary | standard-scientific | delivery | Co-engaged through the Motor system of record: the paradigm engages this system (its core members are graded e |
| bimanual-coordination | stimulator | secondary | standard-scientific | delivery | Co-engaged through the Motor system of record: the paradigm engages this system (its core members are graded e |
| bimanual-coordination | assessor | secondary | standard-scientific | fMRI | Co-engaged through the Motor system of record: the paradigm engages this system (its core members are graded e |
| simple-rt ↗ | inhibitor | secondary | standard-scientific | delivery | Repeated speeded presses train one motor program into an adapted state: the on-disk ALE meta-analysis of 70 mo |
| choice-rt ↗ | inhibitor | secondary | standard-scientific | delivery | Trained choice responses shed errors and co-contraction with practice: the on-disk motor-learning meta-analysi |
Experiences of record: Sequence-tap motor trainer
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| Increased neural activation during picture encoding and retrieval in 60-year-olds compared to 20-year-olds. Neuropsychologia 2010 · 10.1016/j.neuropsychologia.2010.04.011 |
| Striatal dysfunction marks preexisting risk and medial prefrontal dysfunction is related to problem drinking in childre Biological psychiatry 2010 · 10.1016/j.biopsych.2010.02.020 |
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| Remembering beauty: roles of orbitofrontal and hippocampal regions in successful memory encoding of attractive faces. NeuroImage 2011 · 10.1016/j.neuroimage.2010.07.046 |
| Broca's region: linking human brain functional connectivity data and non-human primate tracing anatomy studies. The European journal of neuroscience 2010 · 10.1111/j.1460-9568.2010.07279.x |
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| Functional topography of the cerebellum for motor and cognitive tasks: an fMRI study. NeuroImage 2012 · 10.1016/j.neuroimage.2011.08.065 |
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| Propofol disrupts functional interactions between sensory and high-order processing of auditory verbal memory. Human brain mapping 2012 · 10.1002/hbm.21385 |
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| How does interoceptive awareness interact with the subjective experience of emotion? An fMRI study. Human brain mapping 2013 · 10.1002/hbm.21458 |
| Segregated and overlapping neural circuits exist for the production of static and dynamic precision grip force. Human brain mapping 2013 · 10.1002/hbm.21467 |
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| Decoding effector-dependent and effector-independent movement intentions from human parieto-frontal brain activity. The Journal of neuroscience : the official journal of the Society for Neuroscience 2011 · 10.1523/JNEUROSCI.1058-11.2011 |
| Large-scale brain networks emerge from dynamic processing of musical timbre, key and rhythm. NeuroImage 2012 · 10.1016/j.neuroimage.2011.11.019 |
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| Age-related neural reorganization during spoken word recognition: the interaction of form and meaning. Journal of cognitive neuroscience 2012 · 10.1162/jocn_a_00218 |
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| Individual differences in premotor and motor recruitment during speech perception. Neuropsychologia 2012 · 10.1016/j.neuropsychologia.2012.02.023 |
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| Functional interactions of HIV-infection and methamphetamine dependence during motor programming. Psychiatry research 2012 · 10.1016/j.pscychresns.2012.03.006 |
| fMRI-activation during drawing a naturalistic or sketchy portrait. Behavioural brain research 2012 · 10.1016/j.bbr.2012.05.009 |
| Mechanical flutter stimulation induces a lasting response in the sensorimotor cortex as revealed with BOLD fMRI. Human brain mapping 2013 · 10.1002/hbm.22102 |
| Exposure therapy triggers lasting reorganization of neural fear processing. Proceedings of the National Academy of Sciences of the United States of America 2012 · 10.1073/pnas.1205242109 |
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| Gray matter density of auditory association cortex relates to knowledge of sound concepts in primary progressive aphasi The Journal of neuroscience : the official journal of the Society for Neuroscience 2012 · 10.1523/JNEUROSCI.6241-11.2012 |
| Dissociable influences of opiates and expectations on pain. The Journal of neuroscience : the official journal of the Society for Neuroscience 2012 · 10.1523/JNEUROSCI.0383-12.2012 |
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| Loss of intranetwork and internetwork resting state functional connections with Alzheimer's disease progression. The Journal of neuroscience : the official journal of the Society for Neuroscience 2012 · 10.1523/JNEUROSCI.5698-11.2012 |
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| "Effect of foreknowledge on neural activity of primary ""go"" responses relates to response stopping and switching." Frontiers in human neuroscience 2015 · 10.3389/fnhum.2015.00034 |
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| Autism: reduced connectivity between cortical areas involved in face expression, theory of mind, and the sense of self. Brain : a journal of neurology 2015 · 10.1093/brain/awv051 |
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| Probing the Cognitive Mechanism of Mental Representational Change During Chunk Decomposition: A Parametric fMRI Study. Cerebral cortex (New York, N.Y. : 1991) 2015 · 10.1093/cercor/bhv113 |
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| Neurofunctional Signature of Hyperfamiliarity for Unknown Faces. PloS one 2015 · 10.1371/journal.pone.0129970 |
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| Brain Regions Associated to a Kinesthetic Illusion Evoked by Watching a Video of One's Own Moving Hand. PloS one 2015 · 10.1371/journal.pone.0131970 |
| Age-Related Differences in Spatial Frequency Processing during Scene Categorization. PloS one 2015 · 10.1371/journal.pone.0134554 |
| Muscle co-activity tuning in Parkinsonian hand movement: disease-specific changes at behavioral and cerebral level. Frontiers in human neuroscience 2015 · 10.3389/fnhum.2015.00437 |
| Decoding sequential finger movements from preparatory activity in higher-order motor regions: a functional magnetic reso The European journal of neuroscience 2015 · 10.1111/ejn.13063 |
| Body language in the brain: constructing meaning from expressive movement. Frontiers in human neuroscience 2015 · 10.3389/fnhum.2015.00450 |
| Neurofunctional topography of the human hippocampus. Human brain mapping 2015 · 10.1002/hbm.22987 |
| The Neural Correlates of Shoulder Apprehension: A Functional MRI Study. PloS one 2015 · 10.1371/journal.pone.0137387 |
| SNARC meets SPARC in fMRI--Interdependence of compatibility effects depends on semantic content. Neuropsychologia 2015 · 10.1016/j.neuropsychologia.2015.09.018 |
| Neuroimaging of the joint Simon effect with believed biological and non-biological co-actors. Frontiers in human neuroscience 2015 · 10.3389/fnhum.2015.00483 |
| Abnormal functional integration of thalamic low frequency oscillation in the BOLD signal after acute heroin treatment. Human brain mapping 2015 · 10.1002/hbm.23011 |
| Impaired target detection in schizophrenia and the ventral attentional network: Findings from a joint event-related pote NeuroImage. Clinical 2015 · 10.1016/j.nicl.2015.07.004 |
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| Distinct neural correlates for attention lapses in patients with schizophrenia and healthy participants. Frontiers in human neuroscience 2015 · 10.3389/fnhum.2015.00502 |
| A task-independent neural representation of subjective certainty in visual perception. Frontiers in human neuroscience 2015 · 10.3389/fnhum.2015.00551 |
| Seeing biological actions in 3D: An fMRI study. Human brain mapping 2016 · 10.1002/hbm.23020 |
| Neural substrates of shared attention as social memory: A hyperscanning functional magnetic resonance imaging study. NeuroImage 2016 · 10.1016/j.neuroimage.2015.09.076 |
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| Perception drives production across sensory modalities: A network for sensorimotor integration of visual speech. NeuroImage 2016 · 10.1016/j.neuroimage.2015.11.038 |
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| Detection of Motor Changes in Huntington's Disease Using Dynamic Causal Modeling. Frontiers in human neuroscience 2015 · 10.3389/fnhum.2015.00634 |
| Neural correlates of abnormal sensory discrimination in laryngeal dystonia. NeuroImage. Clinical 2016 · 10.1016/j.nicl.2015.10.016 |
| The Neural Basis of Vocal Pitch Imitation in Humans. Journal of cognitive neuroscience 2016 · 10.1162/jocn_a_00914 |
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| Is Brain Activity during Action Observation Modulated by the Perceived Fairness of the Actor? PloS one 2016 · 10.1371/journal.pone.0145350 |
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| The Cognitive Side of M1. Frontiers in human neuroscience 2016 · 10.3389/fnhum.2016.00298 |
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| Prediction of Biological Motion Perception Performance from Intrinsic Brain Network Regional Efficiency. Frontiers in human neuroscience 2016 · 10.3389/fnhum.2016.00552 |
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| How people with multiple sclerosis cope with a sustained finger motor task: A behavioural and fMRI study. Behavioural brain research 2017 · 10.1016/j.bbr.2017.02.008 |
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| Radiation-induced abnormal cortical thickness in patients with nasopharyngeal carcinoma after radiotherapy. NeuroImage. Clinical 2017 · 10.1016/j.nicl.2017.02.025 |
| Latent and Abnormal Functional Connectivity Circuits in Autism Spectrum Disorder. Frontiers in neuroscience 2017 · 10.3389/fnins.2017.00125 |
| Syntactic Complexity and Frequency in the Neurocognitive Language System. Journal of cognitive neuroscience 2017 · 10.1162/jocn_a_01137 |
| Using guitar learning to probe the Action Observation Network's response to visuomotor familiarity. NeuroImage 2017 · 10.1016/j.neuroimage.2017.04.060 |
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| Local-to-remote cortical connectivity in amnestic mild cognitive impairment. Neurobiology of aging 2017 · 10.1016/j.neurobiolaging.2017.04.016 |
| Behavioural and neural evidence for the impact of fluency context on conscious memory. Cortex; a journal devoted to the study of the nervous system and behavior 2017 · 10.1016/j.cortex.2017.04.008 |
| Reward anticipation revisited- evidence from an fMRI study in euthymic bipolar I patients and healthy first-degree rela Journal of affective disorders 2017 · 10.1016/j.jad.2017.04.044 |
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| Neurobiological correlates of impulsivity in healthy adults: Lower prefrontal gray matter volume and spontaneous eye-bli NeuroImage 2017 · 10.1016/j.neuroimage.2017.06.015 |
| Proximity alert! Distance related cuneus activation in military veterans with anger and aggression problems. Psychiatry research. Neuroimaging 2017 · 10.1016/j.pscychresns.2017.06.012 |
| Neural correlates of prosocial behavior towards persons in pain in healthcare providers. Biological psychology 2017 · 10.1016/j.biopsycho.2017.06.005 |
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| Neural encoding of saltatory pneumotactile velocity in human glabrous hand. PloS one 2017 · 10.1371/journal.pone.0183532 |
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| Effects of Body Mass Index and Body Fat Percent on Default Mode, Executive Control, and Salience Network Structure and F PMID 27378831 |
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| Facing mixed emotions: Analytic and holistic perception of facial emotion expressions engages separate brain networks PMID 27393421 |
| Neural effects of methylphenidate and nicotine during smooth pursuit eye movements PMID 27402599 |
| Atypical within- and between-hemisphere motor network functional connections in children with developmental coordination PMID 27419066 |
| Mapping the cortical representation of speech sounds in a syllable repetition task PMID 27421186 |
| Differential roles for parietal and frontal cortices in fixed versus evolving temporal expectations: Dissociating prior PMID 27431757 |
| The transition from childhood to adolescence is marked by a general decrease in amygdala reactivity and an affect-specif PMID 27445112 |
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| Motor and mental training in older people: Transfer, interference, and associated functional neural responses PMID 27450266 |
| Impact of Short Social Training on Prosocial Behaviors: An fMRI Study PMID 27458349 |
| Regional homogeneity of intrinsic brain activity correlates with auditory-motor processing of vocal pitch errors PMID 27502049 |
| Effect of Mild Thyrotoxicosis on Performance and Brain Activations in a Working Memory Task PMID 27536945 |
| Neural changes associated to procedural learning and automatization process in Developmental Coordination Disorder and/o PMID 27546352 |
| Cortical and subcortical brain alterations in Juvenile Absence Epilepsy PMID 27551668 |
| Accuracy of automated classification of major depressive disorder as a function of symptom severity PMID 27551669 |
| Mediation of episodic memory performance by the executive function network in patients with amnestic mild cognitive impa PMID 27589839 |
| Increased Brain Activation for Dual Tasking with 70-Days Head-Down Bed Rest PMID 27601982 |
| Age-related differences in brain activity during implicit and explicit processing of fearful facial expressions PMID 27614138 |
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| Posterior Superior Temporal Sulcus Responses Predict Perceived Pleasantness of Skin Stroking PMID 27679564 |
| A Pilot Study of Mindfulness-Based Exposure Therapy in OEF/OIF Combat Veterans with PTSD: Altered Medial Frontal Cortex PMID 27703434 |
| The impact of aging on the neural networks involved in gaze and emotional processing PMID 27716474 |
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*Frontal lobe · Mai atlas of record · 1250 studies · 138 papers on disk*
The precentral gyrus is primary motor cortex — the final somatotopically-organized cortical stage for voluntary movement, projecting through the corticospinal tract, running from the paracentral lobule down to the Sylvian fissure in front of the central sulcus.
The precentral gyrus runs parallel to and immediately in front of the central sulcus, from the medial surface (continuous with the paracentral lobule) down toward the Sylvian fissure, bordered behind by the central sulcus and before by the precentral sulcus. Its layer V contains the giant Betz pyramidal cells; together with the posterior bank of the precentral sulcus it forms the primary motor area (Brodmann area 4), anterior to area 6.
*— {'source': 'Mai, Majtanik & Paxinos', 'work': 'Atlas of the Human Brain, 4th ed., Academic Press/Elsevier', 'kind': 'atlas', 'locator': 'axial plates, MNI y −35.1…+10.1 mm, 37 plates (labels PrG)'}*
Primary motor cortex: the final somatotopically organized cortical stage for voluntary movement execution, projecting through the corticospinal tract. Intrinsic-connectivity parcellations place it at the core of the somatomotor network; stimulation evokes focal movements ordered as the motor homunculus. Lesion produces contralateral paresis of the represented body part.
The functional record: voluntary movement execution, tract-projected. The decoded profile is the working body: motor, movement, hand, finger. The graded matrix: simple-RT as a highly-credible assessor, choice-RT as stimulator, finger-sequence-learning as assessor — the reaction-time and sequence family, recorded. Its coactivation map is the sensorimotor loop: central sulcus (1,113 shared studies), premotor/SMA (1,065+1,004), postcentral gyrus (976).
*— {'source': 'Gazzaniga, Ivry & Mangun', 'work': 'Cognitive Neuroscience: The Biology of the Mind, 4th ed., W. W. Norton', 'kind': 'textbook', 'locator': 'ch. 8, Action'}*
*— {'source': 'Yeo, Krienen, Sepulcre et al.', 'work': 'The organization of the human cerebral cortex estimated by intrinsic functional connectivity, J Neurophysiol 2011', 'locator': 'somatomotor network (fcMRI topography within motor and somatosensory cortex)', 'kind': 'paper'}*
The M1 loop: execution, sensation and planning firing together.
Co-activation partners of record: Central sulcus:1113, BA 6 - premotor/SMA:1065, Supplementary motor area:1004, Postcentral gyrus:976, Postcentral sulcus:771, Intraparietal sulcus:739, Cingulate gyrus, anterior:731, Thalamus:649.
Contralateral weakness by somatotopy — the homunculus' motor deficits, from leg (medial, ACA) to face (lateral, MCA). The gyrus's failure-mode is the neurology exam's motor chapter.
10.1016/S0896-6273(00)80593-010.1093/cercor/9.1.3510.1016/S0920-9964(98)00141-81250 studies total touch this region in the Neurosynth corpus of record; the full literature lives beside this dossier.
Candidate levers (Neurosynth-decoded terms — motor(action-motor), movement(action-motor), movements(action-motor), hand(action-motor), premotor(anatomy-reference), finger(action-motor), m1(anatomy-reference), sensorimotor(method-other) …) are the foundation for the thousands of instruments to come; they are ungraded by law.
Central sulcus:1113, BA 6 - premotor/SMA:1065, Supplementary motor area:1004, Postcentral gyrus:976 — each name is a dossier stop in this explorer.