Structure. The optic chiasm is the X-shaped crossing at the hypothalamus' anterior floor where the two optic tracts meet: nasal-retinal fibres decussate (each hemisphere ends up with the OPPOSITE visual field), macular fibres posteriorly, with the infundibulum behind and the internal carotids on either side.
Function. The visual hemifields' crossing point: its Mid-saggital compression (pituitary adenoma from below, craniopharyngioma from above) slices the decussating nasal fibres into the classic bitemporal hemianopia — half of each eye's field, both eyes.
| Instrument | Role | Tier | Credibility | Via | Observed effect |
|---|---|---|---|---|---|
| reward-prediction ↗ | assessor | secondary | standard-scientific | fMRI | On-disk monetary incentive delay fMRI in pathological gambling: ventromedial caudate activation during anticip |
| reward-punishment ↗ | assessor | secondary | standard-scientific | fMRI | On-disk reversal-learning fMRI: medial orbitofrontal activity correlated with the positive affect of feedback |
| igt ↗ | assessor | secondary | standard-scientific | fMRI | On-disk adolescent risk fMRI: 81 youths repeatedly chose a cautious response earning 1 cent or a risky one win |
| facial-emotion | assessor | secondary | standard-scientific | fMRI | On-disk pharmacological fMRI: healthy men's amygdala hemodynamic response to masked sad faces rose under both |
| emotional-stroop ↗ | assessor | secondary | standard-scientific | fMRI | On-disk fMRI of emotional complexity: valenced animations conveyed emotion by motion alone, and attending to s |
| pain-induction | assessor | secondary | standard-scientific | fMRI | Profile-only ground: the region's decoded Neurosynth association ranks pain 11th of 250 terms (0.008), so acti |
| face-identity | stimulator | secondary | standard-scientific | delivery | 'Pictures' (rank 14) is the region's strongest visual-delivery term: face-identity trials present face images |
| cyberball ↗ | stimulator | secondary | standard-scientific | delivery | Profile term 'social' (rank 12) marks this region's held social-task evidence: cyberball is delivered as on-sc |
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| Is morality unified? Evidence that distinct neural systems underlie moral judgments of harm, dishonesty, and disgust. Journal of cognitive neuroscience 2011 · 10.1162/jocn_a_00017 |
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| In vivo evidence of global and focal brain alterations in anorexia nervosa. Psychiatry research 2011 · 10.1016/j.pscychresns.2010.12.008 |
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| Differential neural activity during search of specific and general autobiographical memories elicited by musical cues. Neuropsychologia 2011 · 10.1016/j.neuropsychologia.2011.04.032 |
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| Amygdala hyperactivation and prefrontal hypoactivation in subjects with cognitive vulnerability to depression. Biological psychology 2011 · 10.1016/j.biopsycho.2011.08.007 |
| Dissociable effects of top-down and bottom-up attention during episodic encoding. The Journal of neuroscience : the official journal of the Society for Neuroscience 2011 · 10.1523/JNEUROSCI.0152-11.2011 |
| How does the brain regulate negative bias to stigma? Social cognitive and affective neuroscience 2012 · 10.1093/scan/nsr046 |
| Menstrual cycle variations in the BOLD-response to a number bisection task: implications for research on sex differences Brain research 2011 · 10.1016/j.brainres.2011.08.058 |
| Encoding: the keystone to efficient functioning of verbal short-term memory. Neuropsychologia 2011 · 10.1016/j.neuropsychologia.2011.09.018 |
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| Comparing apples and oranges: using reward-specific and reward-general subjective value representation in the brain. The Journal of neuroscience : the official journal of the Society for Neuroscience 2011 · 10.1523/JNEUROSCI.2218-11.2011 |
| White matter integrity deficits in prefrontal-amygdala pathways in Williams syndrome. NeuroImage 2012 · 10.1016/j.neuroimage.2011.09.065 |
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| Striatal activations signal prediction errors on confidence in the absence of external feedback. NeuroImage 2012 · 10.1016/j.neuroimage.2011.11.058 |
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| Common and distinct neural features of social and non-social reward processing in autism and social anxiety disorder. Social cognitive and affective neuroscience 2014 · 10.1093/scan/nss146 |
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| Reward sensitivity is associated with brain activity during erotic stimulus processing. PloS one 2013 · 10.1371/journal.pone.0066940 |
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| Effects of emotion and emotional valence on the neural correlates of episodic memory search and elaboration. Journal of cognitive neuroscience 2014 · 10.1162/jocn_a_00529 |
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| Childhood physical abuse predicts stressor-evoked activity within central visceral control regions. Social cognitive and affective neuroscience 2015 · 10.1093/scan/nsu073 |
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| Intrinsic brain networks normalize with treatment in pediatric complex regional pain syndrome PMID 25379449 |
| Atypical perception of affective prosody in Autism Spectrum Disorder PMID 25379450 |
| Neural changes associated with the generation of specific past and future events in depression PMID 25447064 |
| Neuronal effects of nicotine during auditory selective attention PMID 25491929 |
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| Mothers know best: redirecting adolescent reward sensitivity toward safe behavior during risk taking PMID 25759470 |
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*Occipital lobe · Mai atlas of record · 368 studies · 147 papers on disk*
The optic chiasm is the X-shaped crossing at the hypothalamus' anterior floor where nasal-retinal fibres decussate — the point where each hemisphere acquires the opposite visual field. Its Mid-saggital compression (pituitary adenoma from below, craniopharyngioma from above) slices the decussating fibres into the classic bitemporal hemianopia.
The optic chiasm is the X-shaped crossing at the hypothalamus' anterior floor where the two optic tracts meet: nasal-retinal fibres decussate (each hemisphere ends up with the OPPOSITE visual field), macular fibres posteriorly, with the infundibulum behind and the internal carotids on either side.
*— {'source': 'Naidich, Duvernoy, Delman, Sorensen, Kollias & Haacke', 'work': "Duvernoy's Atlas of the Human Brain Stem and Cerebellum: High-Field MRI, Springer", 'kind': 'atlas', 'locator': 'ventral diencephalon, optic pathways'}*
The visual hemifields' crossing point: its Mid-saggital compression (pituitary adenoma from below, craniopharyngioma from above) slices the decussating nasal fibres into the classic bitemporal hemianopia — half of each eye's field, both eyes.
The functional record: the visual hemifields' crossing, and the endocrine neighbourhood's casualty. The decoded profile is the chiasm's hypothalamic neighbourhood — reward, amygdala, hypothalamus, striatal, emotional — the optic chiasm sits inside the hypothalamus' reward-and-pituitary anatomy, and its literature overlaps the endocrine one. No graded instrument is assigned — a crossing's levers are the visual field's, tested per quadrant.
*— {'source': 'Gazzaniga, Ivry & Mangun', 'work': 'Cognitive Neuroscience: The Biology of the Mind, 4th ed., W. W. Norton', 'kind': 'textbook', 'locator': 'ch. 5, Sensation and Perception'}*
Amygdala (314 shared studies), subcallosal gyrus (294), the mirror amygdala (253), uncus (231), entorhinal cortex (195) — the chiasm's medial temporal neighbours above the pituitary fossa.
Co-activation partners of record: Amygdala:314, Subcallosal gyrus:294, Amygdala:253, Uncus:231, Entorhinal cortex:195, Third ventricle:190, Rhinal sulcus:184, BA 25 - subgenual cingulate:166.
Bitemporal hemianopia — the crossing's signature lesion, pituitary surgery's constant vigilance. The decoded endocrine vocabulary is the tumour's neighbourhood speaking.
10.1016/S0028-3932(00)00157-310.1073/pnas.07104309810.1016/S1388-2457(02)00026-310.1016/S0006-3223(02)01466-X10.1016/S0006-3223(02)01485-310.1016/S1053-8119(03)00087-9368 studies total touch this region in the Neurosynth corpus of record; the full literature lives beside this dossier.
Candidate levers (Neurosynth-decoded terms — reward(method-other), amygdala(anatomy-reference), hypothalamus(anatomy-reference), striatum(method-other), emotional(emotion), ventral striatum(method-other), sexual(method-other), ventral(method-other) …) are the foundation for the thousands of instruments to come; they are ungraded by law.
Amygdala:314, Subcallosal gyrus:294, Amygdala:253, Uncus:231 — each name is a dossier stop in this explorer.