Structure. The circular sulcus of the insula rings the insular lobe on all sides, separating it from the frontal, parietal and temporal opercula that overlie it; opening the lateral fissure reveals this annular groove enclosing the insular surface.
Function. The insula's surgical boundary: it is the dissection plane between interoceptive insular cortex and opercular sensorimotor/language banks rather than a functional territory itself.
| Instrument | Role | Tier | Credibility | Via | Observed effect |
|---|---|---|---|---|---|
| pain-induction | stimulator | secondary | standard-scientific | delivery | Noxious heat and laser stimuli delivered in fMRI studies engage this insular region: noxious laser pain drove |
| reward-punishment ↗ | assessor | secondary | standard-scientific | fMRI | During a probabilistic reward/punishment learning task under fMRI, induced inflammation biased behavior toward |
| reward-prediction ↗ | assessor | secondary | standard-scientific | fMRI | When visual-search targets appeared at context-predicted locations, activation rose in left posterior putamen |
| cyberball ↗ | assessor | secondary | standard-scientific | fMRI | A Cyberball social-exclusion fMRI study in social anxiety disorder is held in this region's folder: patients r |
| simple-rt ↗ | stimulator | secondary | standard-scientific | delivery | Task-fMRI of paced finger tapping (sensorimotor synchronization to auditory tempo changes) reports left insula |
| nback ↗ | stimulator | secondary | standard-scientific | delivery | Delivering verbal working memory (modified Brown-Peterson encoding/maintenance/retrieval) in fMRI shows left i |
| facial-emotion | assessor | secondary | standard-scientific | fMRI | Event-related fMRI while participants view static neutral, happy and angry facial expressions at high/low inte |
| igt ↗ | assessor | secondary | standard-scientific | fMRI | Event-related fMRI of risky decisions (cautious 1-cent vs risky gain-5/lose-10-cent choices) finds insula amon |
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| Altered resting state cortico-striatal connectivity in mild to moderate stage Parkinson's disease. Frontiers in systems neuroscience 2010 · 10.3389/fnsys.2010.00143 |
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| Cognitive Deterioration and Functional Compensation in ALS Measured with fMRI Using an Inhibitory Task. The Journal of neuroscience : the official journal of the Society for Neuroscience 2014 · 10.1523/JNEUROSCI.1111-14.2014 |
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| The effects of energy balance, obesity-proneness and sex on the neuronal response to sweet taste. Behavioural brain research 2014 · 10.1016/j.bbr.2014.10.024 |
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| Associations between age, motor function, and resting state sensorimotor network connectivity in healthy older adults. NeuroImage 2015 · 10.1016/j.neuroimage.2014.12.023 |
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| The Representation of Object-Directed Action and Function Knowledge in the Human Brain. Cerebral cortex (New York, N.Y. : 1991) 2015 · 10.1093/cercor/bhu328 |
| Neurophysiological effects of sleep deprivation in healthy adults, a pilot study. PloS one 2015 · 10.1371/journal.pone.0116906 |
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| Neurobiological Impact of Nicotinic Acetylcholine Receptor Agonists: An Activation Likelihood Estimation Meta-Analysis o Biological psychiatry 2015 · 10.1016/j.biopsych.2014.12.021 |
| Mirroring pain in the brain: emotional expression versus motor imitation. PloS one 2015 · 10.1371/journal.pone.0107526 |
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| Connectivity and functional profiling of abnormal brain structures in pedophilia. Human brain mapping 2015 · 10.1002/hbm.22777 |
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| Differential cerebral response to somatosensory stimulation of an acupuncture point vs. two non-acupuncture points measu Frontiers in human neuroscience 2015 · 10.3389/fnhum.2015.00074 |
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| Love-related changes in the brain: a resting-state functional magnetic resonance imaging study. Frontiers in human neuroscience 2015 · 10.3389/fnhum.2015.00071 |
| Propensity to obesity impacts the neuronal response to energy imbalance. Frontiers in behavioral neuroscience 2015 · 10.3389/fnbeh.2015.00052 |
| Obesity is marked by distinct functional connectivity in brain networks involved in food reward and salience. Behavioural brain research 2015 · 10.1016/j.bbr.2015.03.016 |
| What can the brain teach us about winemaking? An fMRI study of alcohol level preferences. PloS one 2015 · 10.1371/journal.pone.0119220 |
| Do I know you? Examining face and object memory in frontotemporal dementia. Neuropsychologia 2015 · 10.1016/j.neuropsychologia.2015.03.020 |
| A preliminary fMRI study of a novel self-paced written fluency task: observation of left-hemispheric activation, and in Frontiers in human neuroscience 2015 · 10.3389/fnhum.2015.00113 |
| Age related-changes in the neural basis of self-generation in verbal paired associate learning. NeuroImage. Clinical 2015 · 10.1016/j.nicl.2015.02.006 |
| Dorsal striatum mediates cognitive control, not cognitive effort per se, in decision-making: An event-related fMRI study NeuroImage 2015 · 10.1016/j.neuroimage.2015.03.082 |
| A pilot fMRI study of the effect of stressful factors on the onset of depression in female patients. Brain imaging and behavior 2015 · 10.1007/s11682-015-9382-8 |
| Goal- and retrieval-dependent activity in the striatum during memory recognition. Neuropsychologia 2015 · 10.1016/j.neuropsychologia.2015.04.011 |
| Brain responses to emotional salience and reward in alcohol use disorder. Brain imaging and behavior 2015 · 10.1007/s11682-015-9374-8 |
| Impaired Recognition and Regulation of Disgust Is Associated with Distinct but Partially Overlapping Patterns of Decreas Biological psychiatry 2015 · 10.1016/j.biopsych.2014.12.031 |
| The simple act of choosing influences declarative memory. The Journal of neuroscience : the official journal of the Society for Neuroscience 2015 · 10.1523/JNEUROSCI.4181-14.2015 |
| Grey matter volumes in treatment naive vs. chronically treated children with attention deficit/hyperactivity disorder: a European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 2015 · 10.1016/j.euroneuro.2015.04.015 |
| Symptom severity and disgust-related traits in borderline personality disorder: The role of amygdala subdivisions. Psychiatry research 2015 · 10.1016/j.pscychresns.2015.04.002 |
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| The neural basis of testable and non-testable beliefs. PloS one 2015 · 10.1371/journal.pone.0124596 |
| Slow breathing and hypoxic challenge: cardiorespiratory consequences and their central neural substrates. PloS one 2015 · 10.1371/journal.pone.0127082 |
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| Common and distinct neural effects of risperidone and olanzapine during procedural learning in schizophrenia: a randomis Psychopharmacology 2015 · 10.1007/s00213-015-3959-1 |
| Affective context interferes with brain responses during cognitive processing in borderline personality disorder: fMRI Psychiatry research 2015 · 10.1016/j.pscychresns.2015.04.006 |
| An fMRI investigation into the effect of preceding stimuli during visual oddball tasks. Journal of neuroscience methods 2015 · 10.1016/j.jneumeth.2015.05.005 |
| Sex differences in intrinsic brain functional connectivity underlying human shyness. Social cognitive and affective neuroscience 2015 · 10.1093/scan/nsv052 |
| Autonomic and brain responses associated with empathy deficits in autism spectrum disorder. Human brain mapping 2015 · 10.1002/hbm.22840 |
| Connections between Intraparietal Sulcus and a Sensorimotor Network Underpin Sustained Tactile Attention. The Journal of neuroscience : the official journal of the Society for Neuroscience 2015 · 10.1523/JNEUROSCI.3421-14.2015 |
| Activity in the brain network for dynamic manipulation of unstable objects is robust to acute tactile nerve block: An fM Brain research 2015 · 10.1016/j.brainres.2015.05.016 |
| A single dual-stream framework for syntactic computations in music and language. NeuroImage 2015 · 10.1016/j.neuroimage.2015.05.020 |
| Effects of oxytocin and vasopressin on the neural response to unreciprocated cooperation within brain regions involved i Brain imaging and behavior 2015 · 10.1007/s11682-015-9411-7 |
| Emotion Reactivity Is Increased 4-6 Weeks Postpartum in Healthy Women: A Longitudinal fMRI Study. PloS one 2015 · 10.1371/journal.pone.0128964 |
| Nicotinergic Modulation of Attention-Related Neural Activity Differentiates Polymorphisms of DRD2 and CHRNA4 Receptor Ge PloS one 2015 · 10.1371/journal.pone.0126460 |
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| Increased skin conductance responses and neural activity during fear conditioning are associated with a repressive copin Frontiers in behavioral neuroscience 2015 · 10.3389/fnbeh.2015.00132 |
| May Functional Imaging be Helpful for Behavioral Assessment in Children? Regions of Motor and Associative Cortico-Subco Frontiers in human neuroscience 2015 · 10.3389/fnhum.2015.00314 |
| Neural Substrates for Head Movements in Humans: A Functional Magnetic Resonance Imaging Study. The Journal of neuroscience : the official journal of the Society for Neuroscience 2015 · 10.1523/JNEUROSCI.0851-15.2015 |
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| Neural correlates of biased social fear learning and interaction in an intergroup context. NeuroImage 2015 · 10.1016/j.neuroimage.2015.07.015 |
| Aberrant functioning of the putamen links delusions, antipsychotic drug dose, and compromised connectivity in first epis Psychiatry research 2015 · 10.1016/j.pscychresns.2015.06.008 |
| "What letters can ""learn"" from Arabic digits--fMRI-controlled single case therapy study of peripheral agraphia." Brain and language 2015 · 10.1016/j.bandl.2015.06.003 |
| Response control networks are selectively modulated by attention to rare events and memory load regardless of the need f NeuroImage 2015 · 10.1016/j.neuroimage.2015.07.026 |
| Modulation of Craving Related Brain Responses Using Real-Time fMRI in Patients with Alcohol Use Disorder. PloS one 2015 · 10.1371/journal.pone.0133034 |
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| Brain Regions Associated to a Kinesthetic Illusion Evoked by Watching a Video of One's Own Moving Hand. PloS one 2015 · 10.1371/journal.pone.0131970 |
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| A Neurocomputational Account of How Inflammation Enhances Sensitivity to Punishments Versus Rewards. Biological psychiatry 2016 · 10.1016/j.biopsych.2015.07.018 |
| Neurobiological underpinnings of sensation seeking trait in heroin abusers. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 2015 · 10.1016/j.euroneuro.2015.07.023 |
| Hippocampal-DMN disconnectivity in MS is related to WM lesions and depression. Human brain mapping 2015 · 10.1002/hbm.22992 |
| The integration of the internal and external milieu in the insula during dynamic emotional experiences. NeuroImage 2016 · 10.1016/j.neuroimage.2015.08.078 |
| Do intuitive and deliberate judgments rely on two distinct neural systems? A case study in face processing. Frontiers in human neuroscience 2015 · 10.3389/fnhum.2015.00456 |
| Alteration of Basal Ganglia and Right Frontoparietal Network in Early Drug-Naive Parkinson's Disease during Heat Pain S Frontiers in human neuroscience 2015 · 10.3389/fnhum.2015.00467 |
| The DA antagonist tiapride impairs context-related extinction learning in a novel context without affecting renewal. Frontiers in behavioral neuroscience 2015 · 10.3389/fnbeh.2015.00238 |
| Neuroimaging of the joint Simon effect with believed biological and non-biological co-actors. Frontiers in human neuroscience 2015 · 10.3389/fnhum.2015.00483 |
| Repetition-Related Reductions in Neural Activity during Emotional Simulations of Future Events. PloS one 2015 · 10.1371/journal.pone.0138354 |
| Physical attractiveness and sex as modulatory factors of empathic brain responses to pain. Frontiers in behavioral neuroscience 2015 · 10.3389/fnbeh.2015.00236 |
| Altered connectivity of the dorsal and ventral visual regions in dyslexic children: a resting-state fMRI study. Frontiers in human neuroscience 2015 · 10.3389/fnhum.2015.00495 |
| fMRI investigation of response inhibition, emotion, impulsivity, and clinical high-risk behavior in adolescents. Frontiers in systems neuroscience 2015 · 10.3389/fnsys.2015.00124 |
| Is it me? Verbal self-monitoring neural network and clinical insight in schizophrenia. Psychiatry research 2015 · 10.1016/j.pscychresns.2015.10.007 |
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| Neuroanatomical Correlates of Theory of Mind Deficit in Parkinson's Disease: A Multimodal Imaging Study. PloS one 2015 · 10.1371/journal.pone.0142234 |
| Altered sensitization patterns to sweet food stimuli in patients recovered from anorexia and bulimia nervosa. Psychiatry research 2015 · 10.1016/j.pscychresns.2015.10.010 |
| When the brain does not adequately feel the body: Links between low resilience and interoception. Biological psychology 2016 · 10.1016/j.biopsycho.2015.11.004 |
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| Increased Frontal Response May Underlie Decreased Tinnitus Severity. PloS one 2015 · 10.1371/journal.pone.0144419 |
| Influence of the cortical midline structures on moral emotion and motivation in moral decision-making. Behavioural brain research 2016 · 10.1016/j.bbr.2016.01.001 |
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| Modulation of hand motor-related area during motor imagery and motor execution before and after middle 2/5 of the MS6 li Brain and cognition 2016 · 10.1016/j.bandc.2016.01.002 |
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| Evaluating cognitive models of visual word recognition using fMRI: Effects of lexical and sublexical variables. NeuroImage 2016 · 10.1016/j.neuroimage.2016.01.013 |
| Ventral and Dorsal Striatum Networks in Obesity: Link to Food Craving and Weight Gain. Biological psychiatry 2017 · 10.1016/j.biopsych.2015.11.020 |
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| Importance of human right inferior frontoparietal network connected by inferior branch of superior longitudinal fascicul Cortex; a journal devoted to the study of the nervous system and behavior 2016 · 10.1016/j.cortex.2016.01.017 |
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| Studying Sub-Dendrograms of Resting-State Functional Networks with Voxel-Wise Hierarchical Clustering. Frontiers in human neuroscience 2016 · 10.3389/fnhum.2016.00075 |
| Memory and functional brain differences in a national sample of U.S. veterans with Gulf War Illness. Psychiatry research. Neuroimaging 2016 · 10.1016/j.pscychresns.2016.03.004 |
| Plastic modulation of episodic memory networks in the aging brain with cognitive decline. Behavioural brain research 2016 · 10.1016/j.bbr.2016.04.022 |
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| fMRI-constrained source analysis reveals early top-down modulations of interference processing using a flanker task. NeuroImage 2016 · 10.1016/j.neuroimage.2016.05.036 |
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| Outcome Uncertainty and Brain Activity Aberrance in the Insula and Anterior Cingulate Cortex Are Associated with Dysfunc Frontiers in human neuroscience 2016 · 10.3389/fnhum.2016.00207 |
| Identifying grey matter changes in schizotypy using partial least squares correlation. Cortex; a journal devoted to the study of the nervous system and behavior 2016 · 10.1016/j.cortex.2016.04.011 |
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| Sampling over Nonuniform Distributions: A Neural Efficiency Account of the Primacy Effect in Statistical Learning. Journal of cognitive neuroscience 2016 · 10.1162/jocn_a_00990 |
| Striatal activation reflects urgency in perceptual decision making. NeuroImage 2016 · 10.1016/j.neuroimage.2016.06.045 |
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| What Impact does An Angry Context have Upon Us? The Effect of Anger on Functional Connectivity of the Right Insula and S Frontiers in behavioral neuroscience 2016 · 10.3389/fnbeh.2016.00109 |
| Demonstration and validation of a new pressure-based MRI-safe pain tolerance device. Journal of neuroscience methods 2016 · 10.1016/j.jneumeth.2016.07.001 |
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| Imaging Imageability: Behavioral Effects and Neural Correlates of Its Interaction with Affect and Context. Frontiers in human neuroscience 2016 · 10.3389/fnhum.2016.00346 |
| Associations of limbic-affective brain activity and severity of ongoing chronic arthritis pain are explained by trait an NeuroImage. Clinical 2016 · 10.1016/j.nicl.2016.06.022 |
| Brain networks of temporal preparation: A multiple regression analysis of neuropsychological data. NeuroImage 2016 · 10.1016/j.neuroimage.2016.08.017 |
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| Posterior Superior Temporal Sulcus Responses Predict Perceived Pleasantness of Skin Stroking. Frontiers in human neuroscience 2016 · 10.3389/fnhum.2016.00432 |
| Neural stress reactivity relates to smoking outcomes and differentiates between mindfulness and cognitive-behavioral tre NeuroImage 2017 · 10.1016/j.neuroimage.2016.09.042 |
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| "Broca Pars Triangularis Constitutes a ""Hub"" of the Language-Control Network during Simultaneous Language Translation. Frontiers in human neuroscience 2016 · 10.3389/fnhum.2016.00491 |
| Difference in Activity in the Supplementary Motor Area Depending on Limb Combination of Hand-Foot Coordinated Movements. Frontiers in human neuroscience 2016 · 10.3389/fnhum.2016.00499 |
| Neural correlates of specific musical anhedonia. Proceedings of the National Academy of Sciences of the United States of America 2016 · 10.1073/pnas.1611211113 |
| Neural Correlates of Hostile Jokes: Cognitive and Motivational Processes in Humor Appreciation. Frontiers in human neuroscience 2016 · 10.3389/fnhum.2016.00527 |
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| Hormone therapy at early post-menopause increases cognitive control-related prefrontal activity PMID 28322310 |
| Correlates of Social Exclusion in Social Anxiety Disorder: An fMRI study PMID 28325901 |
| Long‐term white matter tract reorganization following prolonged febrile seizures PMID 28332711 |
| Combination of volume and perfusion parameters reveals different types of grey matter changes in schizophrenia PMID 28348393 |
| Activation and Functional Connectivity of the Left Inferior Temporal Gyrus during Visual Speech Priming in Healthy Liste PMID 28360829 |
| A neural network underlying intentional emotional facial expression in neurodegenerative disease PMID 28373956 |
| The Rewarding Effect of Pictures with Positive Emotional Connotation upon Perception and Processing of Pleasant Odors—An PMID 28377697 |
| Intrinsic functional connectivity of the central nucleus of the amygdala and bed nucleus of the stria terminalis PMID 28392491 |
| The brain anatomy of attention-deficit/hyperactivity disorder in young adults – a magnetic resonance imaging study PMID 28406942 |
| Basic taste processing recruits bilateral anteroventral and middle dorsal insulae: An activation likelihood estimation m PMID 28413706 |
| Family history and APOE4 risk for Alzheimer's disease impact the neural correlates of episodic memory by early midlife PMID 28413778 |
| Working Memory after Traumatic Brain Injury: The Neural Basis of Improved Performance with Methylphenidate PMID 28424597 |
| Neural dynamics underlying varying attentional control facing invariant cognitive task upon invariant stimuli PMID 28450264 |
| A predictive coding account of bistable perception - a model-based fMRI study PMID 28505152 |
| Molecular imaging of serotonin degeneration in mild cognitive impairment PMID 28511918 |
| Long-Time Exposure to Violent Video Games Does Not Show Desensitization on Empathy for Pain: An fMRI Study PMID 28512439 |
| Functional connectivity in incarcerated male adolescents with psychopathic traits PMID 28521281 |
| Strategy‐based reasoning training modulates cortical thickness and resting‐state functional connectivity in adults with PMID 28523229 |
| Assessing the Psychedelic “After-Glow” in Ayahuasca Users: Post-Acute Neurometabolic and Functional Connectivity Changes PMID 28525587 |
| Changes in resting state functional brain connectivity and withdrawal symptoms are associated with acute electronic ciga PMID 28528203 |
| Frontal and subcortical grey matter reductions in PTSD PMID 28549317 |
| Anatomical Modularity of Verbal Working Memory? Functional Anatomical Evidence from a Famous Patient with Short-Term Mem PMID 28567009 |
| Differences and Similarities for Spatial and Feature-Based Selective Attentional Orienting PMID 28572756 |
| Prenatal manganese exposure and intrinsic functional connectivity of emotional brain areas in children PMID 28610744 |
| Regional impairment of intrinsic functional connectivity strength in patients with chronic primary insomnia PMID 28652745 |
| Proximity alert! Distance related cuneus activation in military veterans with anger and aggression problems PMID 28654776 |
| Functional and structural changes in gray matter of parkinson's disease patients with mild cognitive impairment PMID 28668411 |
| Spatiotemporal neural characterization of prediction error valence and surprise during reward learning in humans PMID 28684734 |
| The Difference of Neural Networks between Bimanual Antiphase and In-Phase Upper Limb Movements: A Preliminary Functional PMID 28701822 |
| Functional Connectivity Differences in the Insular Sub-regions in Migraine without Aura: A Resting-State Functional Magn PMID 28701932 |
| Reduced Pain Sensation and Reduced BOLD Signal in Parietofrontal Networks during Religious Prayer PMID 28701940 |
| Examining distinct working memory processes in children and adolescents using fMRI: Results and validation of a modified PMID 28704424 |
| Illuminating the conceptual structure of the space of moral violations with searchlight representational similarity anal PMID 28743459 |
| Neural correlates of evaluating self and close-other in physical, academic and prosocial domains PMID 28759780 |
| Learning Predictive Statistics: Strategies and Brain Mechanisms PMID 28760866 |
| Effect of Continuous Touch on Brain Functional Connectivity Is Modified by the Operator’s Tactile Attention PMID 28775685 |
| Resting-state functional connectivity changes due to acute and short-term valproic acid administration in the baboon mod PMID 28794974 |
| The effect of visual parameters on neural activation during nonsymbolic number comparison and its relation to math compe PMID 28801254 |
| Neurological evaluation of the selection stage of metaphor comprehension in individuals with and without autism spectrum PMID 28802915 |
| Treatment Associated Changes of Functional Connectivity of Midbrain/Brainstem Nuclei in Major Depressive Disorder PMID 28819132 |
| The levels of perceptual processing and the neural correlates of increasing subjective visibility PMID 28823896 |
| Tone-grammar association within words: Concurrent ERP and fMRI show rapid neural pre-activation and involvement of left PMID 28850882 |
| Increased emotional reactivity to affective pictures in patients with skin-picking disorder: Evidence from functional ma PMID 28866131 |
| Probabilistic inference under time pressure leads to a cortical-to-subcortical shift in decision evidence integration PMID 28882633 |
| Cognition in patients with benign epilepsy with centrotemporal spikes: A study with long-term VEEG and RS-fMRI PMID 28882722 |
| Neural correlates of working memory in children and adolescents with agenesis of the corpus callosum: An fMRI study PMID 28893526 |
| Alterations of Brain Functional Architecture Associated with Psychopathic Traits in Male Adolescents with Conduct Disord PMID 28900210 |
| Investigating the Neural Correlates of Emotion–Cognition Interaction Using an Affective Stroop Task PMID 28919871 |
*Temporal lobe · Mai atlas of record · 1118 studies · 158 papers on disk*
The circular sulcus is the moat around the insula — the annular groove separating the interoceptive island from the opercular banks that bury it. It is a surgeon's landmark before it is anything functional.
The circular sulcus of the insula rings the insular lobe on all sides, separating it from the frontal, parietal and temporal opercula that overlie it; opening the lateral fissure reveals this annular groove enclosing the insular surface.
*— {'source': 'Mai, Majtanik & Paxinos', 'work': 'Atlas of the Human Brain, 4th ed., Academic Press/Elsevier', 'kind': 'atlas', 'locator': 'axial plates, MNI y −43.7…+7.2 mm, 12 plates (labels cis)'}*
The insula's surgical boundary: it is the dissection plane between interoceptive insular cortex and opercular sensorimotor/language banks rather than a functional territory itself.
The functional record says exactly that: the dissection plane between interoceptive insular cortex and the opercular sensorimotor/language banks. Its decoded profile — pain, insula, motor, putamen — reflects the structures it touches rather than a function it owns. The adjacency harvest gave this dossier its literature; no graded instrument is assigned — boundaries don't carry levers.
*— {'source': 'Gazzaniga, Ivry & Mangun', 'work': 'Cognitive Neuroscience: The Biology of the Mind, 4th ed., W. W. Norton', 'kind': 'textbook', 'locator': 'ch. 5, Sensation and Perception'}*
Insular cortex (1,550 shared studies), claustrum (1,346), putamen (1,033), lateral fissure (901) — the island and the banks it separates, co-activating by definition.
Co-activation partners of record: Insular cortex:1550, Claustrum:1346, Putamen:1033, Lateral fissure:901, Cingulate gyrus, anterior:732, Insular cortex:686, Globus pallidus, external segment:653, Thalamus:647.
Its failure-mode is surgical: the insula's resection margin. The moat's importance is measured in millimetres not walked by the scalpel.
Reading this dossier's coactivation map is a tour of what the moat touches: the insular cortex within (1,550 shared studies), the claustrum beyond (1,346), the putamen's lateral rim (1,033) — every structure a surgeon must respect when the lateral fissure opens. The tagged profile follows the same geography: pain and insular terms from the island, motor and striatal terms from the banks.
10.1093/cercor/9.7.66210.1093/cercor/10.6.5521118 studies total touch this region in the Neurosynth corpus of record; the full literature lives beside this dossier.
Candidate levers (Neurosynth-decoded terms — pain(interoception), insula(anatomy-reference), motor(action-motor), insular(anatomy-reference), stimulation(method-other), somatosensory(method-other), putamen(anatomy-reference), striatum(method-other) …) are the foundation for the thousands of instruments to come; they are ungraded by law.
Insular cortex:1550, Claustrum:1346, Putamen:1033, Lateral fissure:901 — each name is a dossier stop in this explorer.