Structure. The putamen is the striatum's large lateral egg, lying between the external capsule (laterally) and the globus pallidus (medially), fused to the caudate head anteriorly; together they form the lentiform complex's outer dark mass — the neostriatum's motor-dominant division.
Function. Skeletal-motor selection's somatotopic hub: cortical sensorimotor loops converge here and return through pallidum-thalamus to premotor machinery; dopamine loss in the posterior putamen IS Parkinson's motor signature, and its lateral-edge lesions underlie hemiballism's violent contralateral flinging when the subthalamic loop breaks.
| Instrument | Role | Tier | Credibility | Via | Observed effect |
|---|---|---|---|---|---|
| reward-punishment ↗ | stimulator | secondary | standard-scientific | delivery | Co-engaged through the Reward system (mesocorticolimbic) of record: the paradigm engages this system (its core |
| reward-punishment ↗ | assessor | secondary | standard-scientific | fMRI | Co-engaged through the Reward system (mesocorticolimbic) of record: the paradigm engages this system (its core |
| reward-prediction ↗ | stimulator | secondary | standard-scientific | delivery | Co-engaged through the Reward system (mesocorticolimbic) of record: the paradigm engages this system (its core |
| reward-prediction ↗ | assessor | secondary | standard-scientific | fMRI | Co-engaged through the Reward system (mesocorticolimbic) of record: the paradigm engages this system (its core |
| igt ↗ | stimulator | secondary | standard-scientific | delivery | Co-engaged through the Reward system (mesocorticolimbic) of record: the paradigm engages this system (its core |
| igt ↗ | assessor | secondary | standard-scientific | fMRI | Co-engaged through the Reward system (mesocorticolimbic) of record: the paradigm engages this system (its core |
| taskswitching ↗ | stimulator | secondary | standard-scientific | delivery | Event-related cognitive set-shifting: right putamen (Talairach 26 -9 11, 1147 mm3) appears among activated reg |
| taskswitching ↗ | assessor | secondary | standard-scientific | fMRI | Set-shifting fMRI tables list right putamen (26 -9 11) among suprathreshold activations during response select |
| simple-rt ↗ | stimulator | secondary | standard-scientific | delivery | Healthy controls performing unimanual/bimanual finger-to-thumb movements show right-putamen activation (contro |
| simple-rt ↗ | assessor | secondary | standard-scientific | fMRI | During a finger-to-thumb movement task in the scanner, right putamen BOLD differentiates controls from PD pati |
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| Neural substrates of letter fluency processing in young adults who were born very preterm: alterations in frontal and st NeuroImage 2009 · 10.1016/j.neuroimage.2009.04.041 |
| Evidence for long-range feedback in target detection: Detection of semantic targets modulates activity in early visual a Neuropsychologia 2009 · 10.1016/j.neuropsychologia.2009.02.011 |
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| Cerebral control of the lower urinary tract: how age-related changes might predispose to urge incontinence. NeuroImage 2009 · 10.1016/j.neuroimage.2009.04.087 |
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| Brain activation in an involuntary human action. Brain research 2009 · 10.1016/j.brainres.2009.09.092 |
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| The integration of large-scale neural network modeling and functional brain imaging in speech motor control. NeuroImage 2010 · 10.1016/j.neuroimage.2009.10.023 |
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| Shared neural resources between left and right interlimb coordination skills: the neural substrate of abstract motor rep NeuroImage 2010 · 10.1016/j.neuroimage.2009.10.052 |
| Alertness in young healthy subjects: an fMRI study of brain region interactivity enhanced by a warning signal. Brain and cognition 2010 · 10.1016/j.bandc.2009.09.010 |
| Interactions between cognition and motivation during response inhibition. Neuropsychologia 2010 · 10.1016/j.neuropsychologia.2009.10.017 |
| Sub-cortical and brainstem sites associated with chemo-stimulated increases in ventilation in humans. NeuroImage 2010 · 10.1016/j.neuroimage.2009.11.007 |
| Using perfusion MRI to measure the dynamic changes in neural activation associated with tonic muscular pain. Pain 2010 · 10.1016/j.pain.2009.10.003 |
| Neural correlates of response inhibition in pediatric bipolar disorder and attention deficit hyperactivity disorder. Psychiatry research 2010 · 10.1016/j.pscychresns.2009.07.002 |
| Automated detection of brain atrophy patterns based on MRI for the prediction of Alzheimer's disease. NeuroImage 2010 · 10.1016/j.neuroimage.2009.11.046 |
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| Structural neuroplasticity in the sensorimotor network of professional female ballet dancers. Human brain mapping 2010 · 10.1002/hbm.20928 |
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| Correlation between quantitative EEG and MRI in idiopathic generalized epilepsy. Human brain mapping 2010 · 10.1002/hbm.20944 |
| High-field FMRI reveals brain activation patterns underlying saccade execution in the human superior colliculus. PloS one 2010 · 10.1371/journal.pone.0008691 |
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*Frontal lobe · Mai atlas of record · 1067 studies · 150 papers on disk*
The right putamen — the mirror egg. Same somatotopic motor selection, same dopaminergic stakes, and its coactivation map is the tightest striatal-claustrum sandwich in the atlas: claustrum (1,247+816 shared studies) firing with the putamen on both sides.
The putamen is the striatum's large lateral egg, lying between the external capsule (laterally) and the globus pallidus (medially), fused to the caudate head anteriorly; together they form the lentiform complex's outer dark mass — the neostriatum's motor-dominant division.
*— {'source': 'Naidich, Duvernoy, Delman, Sorensen, Kollias & Haacke', 'work': "Duvernoy's Atlas of the Human Brain Stem and Cerebellum: High-Field MRI, Springer", 'kind': 'atlas', 'locator': 'basal ganglia, internal structure'}*
Skeletal-motor selection's somatotopic hub: cortical sensorimotor loops converge here and return through pallidum-thalamus to premotor machinery; dopamine loss in the posterior putamen IS Parkinson's motor signature, and its lateral-edge lesions underlie hemiballism's violent contralateral flinging when the subthalamic loop breaks.
The functional record mirrors the left's: sensorimotor loops converged, dopamine-gated selection, posterior dopamine loss as bradykinesia. The decoded profile adds reward to the motor vocabulary. No graded instrument is assigned to this dossier yet — the family's records live on the left twin; the right putamen's own grading is an open slot.
*— {'source': 'Gazzaniga, Ivry & Mangun', 'work': 'Cognitive Neuroscience: The Biology of the Mind, 4th ed., W. W. Norton', 'kind': 'textbook', 'locator': 'ch. 8, Action'}*
The claustrum-putamen-pallidum sandwich, drawn as the atlas's densest subcortical coactivation cluster.
Co-activation partners of record: Claustrum:1247, Globus pallidus, external segment:1071, Putamen:1052, Globus pallidus, external segment:837, Claustrum:816, Supplementary motor area:778, Thalamus:739, Thalamus:664.
The mirror motor story: bradykinesia, dystonia, habit circuits. The right putamen's asymmetries in the dopamine literature remain an open question, recorded as such.
The mirror egg's habit literature adds a twist: the right putamen's dopamine signal tracks reward prediction in some paradigms the left's does not — asymmetries in striatal lateralization remain an active question, recorded here as an open one. Its 150-paper dossier matches its twin's depth.
10.1016/S0896-6273(00)80475-410.1016/S0896-6273(00)80715-110.1016/S0006-3223(99)00083-91067 studies total touch this region in the Neurosynth corpus of record; the full literature lives beside this dossier.
Candidate levers (Neurosynth-decoded terms — motor(action-motor), putamen(anatomy-reference), movement(action-motor), movements(action-motor), basal ganglia(anatomy-reference), ganglia(anatomy-reference), basal(anatomy-reference), reward(method-other) …) are the foundation for the thousands of instruments to come; they are ungraded by law.
Claustrum:1247, Globus pallidus, external segment:1071, Putamen:1052, Globus pallidus, external segment:837 — each name is a dossier stop in this explorer.